Anal gland cancer

Dogs and cats can function normally without these scent glands. Cancer can develop in the anal sac glands in dogs, but rarely in cats. In most cases, this tumor affects only one anal sac, but occasionally both left and right sacs are affected. Anal sac cancer is usually malignant and has a high tendency to spread to the other body parts.
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Anal Sac Tumors

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Anal sac tumours (carcinoma of the apocrine glands of the anal sac) Information Sheet

A year-old Hispanic man presented to the Jackson Memorial Hospital Emergency Room with hematochezia of 6 months duration. He was diagnosed with hemorrhoids and treated with rubber band ligation twice. He had lost 20 pounds in 6 months and had not had a bowel movement for 12 days. On physical exam, he was pale and noted to have a large low rectal lesion. A computed tomography CT scan revealed a large rectal lesion with multiple small perirectal lymph nodes, the largest one measuring approximately 1. A colonoscopy showed a large mass in the lower end of the rectum, and a biopsy revealed mostly necrotic tissue. The mass was excised transanally, and the histological examination revealed a very poorly differentiated adenocarcinoma Figure 1.
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Submit Case Report

Cytology from fine needle aspirate of an anal sac adenocarcinoma. Typical epithelial cell clustering is noted. Anal gland adenocarcinoma AGA also known as apocrine gland anal sac carcinoma adenocarcinoma or anal sac adenocarcinoma is an uncommon cancer that arises from the apocrine glands in the walls of the anal sacs. This type of cancer tends to occur in middle aged to older dogs with many reports showing Cocker spaniels to be a breed at increased risk. Springer spaniels and Cavalier King Charles spaniels were also shown to be at increased risk.
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The inner lining of the anal canal is the mucosa. Most anal cancers start from cells in the mucosa. Glands and ducts tubes leading from the glands are found under the mucosa.
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